COMPOSITION:
Each film-coated tablet contains:
Bilastine ……………… 20 mg
Montelukast ……….. 10 mg
SUMMARY:
Bilastine is a non-sedating, long-acting H1 receptor selective antagonist. Its effects are mediated through the selective inhibition of peripheral H1-receptors. Bilastine demonstrates moderate to high affinity for histamine H1-receptors and shows no affinity for muscarinic, serotonergic, dopaminergic, or noradrenergic receptors. It effectively inhibits histamine-induced flare skin reactions for up to 24 hours following a single dose.
Montelukast is a medication primarily used to manage asthma and allergic rhinitis. It belongs to a class of drugs known as leukotriene receptor antagonists. By blocking leukotrienes, chemicals in the body that cause inflammation and constriction of airways, Montelukast helps reduce asthma symptoms and prevent allergic reactions.
INDICATIONS:
It is indicated for the symptomatic relief of symptoms of allergic rhinitis with or without asthma.
DOSAGE AND ADMINISTRATION:
Dosage – once daily. To achieve optimal exposure to Bilastine, once daily dose should be taken with water on an empty stomach.
CONTRAINDICATIONS:
Bilastine is contraindicated in patients with hypersensitivity to Bilastine or to any ingredient in the formulation or component.
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