COMPOSITION:
DAPASIS 5:
Each tablet contains Dapagliflozin Propanediol Monohydrate equivalent to Dapagliflozin 5 mg.
DAPASIS 10:
Each tablet contains Dapagliflozin Propanediol Monohydrate equivalent to Dapagliflozin 10 mg tablet.
Mechanism of Action:
Sodium-glucose cotransporter 2 (SGLT2), expressed in the proximal renal tubules, is responsible for the majority of the reabsorption of filtered glucose from the tubular lumen. Dapagliflozin is an inhibitor of SGLT2. By inhibiting SGLT2, dapagliflozin reduces reabsorption of filtered glucose and lowers the renal threshold for glucose, and thereby increases urinary glucose excretion.